The Department of Cancer Registry and Epidemiology was started in the year 2010 with the establishment of Hospital Based Cancer Registry (HBCR) at the institute. In 2015, the Epidemiology division was started. Subsequently, in 2018, molecular epidemiology on Genome Wide Association researches was started in collaboration Center for Cancer Epidemiology at Tata Memorial Center, Mumbai. In 2022, a landmark collaborative research under Department of Cancer Registry and Epidemiology, this showed strong association between Arsenic in potable water and gallbladder cancer risk.