Research Activities

The Head & Neck Oncology department at Dr. Bhubaneswar Borooah Cancer Institute (DR BBCI) is at the forefront of cutting-edge research endeavors. With a dedicated team of researchers and clinicians, the department is actively engaged in a spectrum of research activities aimed at advancing our understanding of head and neck cancers. These initiatives encompass clinical trials evaluating novel therapies, translational research efforts to bridge the gap between laboratory discoveries and patient care, and epidemiological studies to gain insights into the prevalence and risk factors associated with head and neck malignancies. Additionally, the department collaborates extensively with national and international institutions, fostering a dynamic research environment that continually contributes to the development of innovative treatment modalities and improved outcomes for patients afflicted with head and neck cancers.

Ongoing research projects:

1. Phase III Randomized control "Adjuvant Radiotherapy in early stage oral cancer (AREST Trial)
2. Identify the DNA Adduct and Associated Metabolic Alterations in Upper Aerodigestive Tract Cancer with Smokeless Tobacco Chewers in the Northeast Region of India: A Metabolomics Approach
3. Image based clinical assessment of oral cancer using Artificial Intelligence
4. A prospective phase iii open labeled Randomized control trial evaluation the role of Neo-adjuvant chemotherapy in mandible preservation in Oral cavity cancer.
5. A non-randomised matched pair prospective study to evaluate nutritional assessment and its impact on postoperative outcome in Head and Neck cancer.
6. Urinary Metabolomics Identified Metabolic Perturbations Associated with Gutka, a Smokeless Form of Tobacco.
7. Effect of Yoga on Quality of Life in patients undergoing Radiotherapy.
8. Genome Wide Association Study to identify role of genetic susceptibility in buccal mucosa cancer.
9. Development of wireless portable potentiostat for non invasive and point of care detection of tobacco related cancer.
10. Evaluation of DNA damage response gene protein expression in hypopharyngeal and laryngeal cancer patients of North East India: with clinical significance with radiotherapy outcome.
11. Worst Pattern of Invasion as an independent prognostic factor in Oral Squamous Cell Carcinoma
12. Incidence, Patterns, and Predisposing Factors of Treatment Induced Head and Neck Lymphedema in Patients Undergoing Curative Treatment for Oral Cavity Malignancies: A Single Institution Based Prospective Study.